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HESI Genomics Committee Publications

It is HESI’s mission to make the results of its scientific activities available in the public domain. The HESI Genomic’s Committee published the following peer-reviewed articles in a Special Mini-Monograph Edition of EHP Toxicogenomics in March 2004 that detail the results of their collaborative experimental program from 2000-2004.

Akerman GS, Rosenzweib BA, Domon OE, McGarrity LJ, Blankenship LR, Tsai CA, Culp SJ, MacGregor JT, Sistare FD, Chen JJ, Morris SM.  Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells.  Mutation Research, 549:43-64. Volume 549, Issue 1-2, 18. May 2004

Amin RP, Vickers AE, Sistare F, Thompson KL, Roman RJ, Lawton M, Kramer J, Hamadeh HK, Collins J, Grissom S, Bennett L, Tucker CJ, Wild S, Kind C, Oreffo V, Davis II JW, Curtiss S, Naciff JM, Cunningham M, Tennant R, Stevens J, Car B, Bertram TA, Afshari CA.. Identification of Putative Gene Based Markers of Renal Toxicity. Environmental Health Perspective Toxicogenomics, 112:465-479.  2004 
 
Baker VA, Harries HM, Waring JF, Duggan CM, Ni HA, Jolly RA, Yoon LW, De Souza AT, Schmid JE, Brown RH, Ulrich RGand Rockett JC. Clofibrate-Induced Gene Expression Changes in Rat Liver: A Cross-Laboratory Analysis Using Membrane cDNA Arrays.  Environmental Health Perspective Toxicogenomics, 112:428-438.  2004
 
Chu TM, Deng S, Wolfinger R, Paules RS, Hamadeh HK. Cross-Site Comparison of Gene Expression Data Reveals High Similarity. Environmental Health Perspective Toxicogenomics, 112:449-455. 2004
 
Dickinson DA, Warnes GR, Quievryn G, Messer J, Zhitkovich A, Rubitski E, Aubrecht J.  Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile analysis.  Mutation Research, 549: 29-41. Volume 549, Issue 1-2, 18. May 2004

Hu T, Gibson DP, Carr GJ, Torontali SM, Tiesman JP, Chaney JG, and Aardema MJ.    Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins.  Mutation Research, 549:5-27. Volume 549, Issue 1-2, 18. May 2004

Kramer JA, Pettit SD, Amin RP, Bertram TA, Car B, Cunningham M, Curtiss SW, Davis JW, Kind C, Lawton M, Naciff JM, Oreffo V, Roman RJ, Sistare FD, Stevens J, Thompson K, Vickers AE, Wild S, and Afshari CA. Overview on the Application of Transcription Profiling using Selected Nephrotoxicants for Toxicology Assessment.  Environmental Health Perspective Toxicogenomics,112:460-464. 2004
 
Newton RK, Aardema M and Aubrecht J. The Utility of DNA Microarrays for Characterizing Genotoxicity. Environmental Health Perspective Toxicogenomics, 112:420-422.  2004
 
Mattes WB. Annotation and Cross-Indexing of Array Elements on Multiple Platforms. Environmental Health Perspective Toxicogenomics, 112:506-510. 2004
 
Mattes WB, Pettit SD, Sansone SA, Bushel PR, and Waters MD. 2004.  Database Development in Toxicogenomics: Issues and Efforts. Environmental Health Perspective Toxicogenomics, 112:495-505. 2004
 
Pennie W, Pettit SD, and Lord PG. 2004. Toxicogenomics in Risk Assessment: an Overview of an ILSI HESI Collaborative Research Program. Environmental Health Perspective Toxicogenomics, 112:417-419. 2004
 
Pettit, S.  "Toxicogenomics in Risk Assessment: Communicating the Challenges."  EHP Toxicogenomics.  2004 (in press).

Rosenzweig BA, Pine PS, Domon OE, Morris SM, Chen JJ, and Sistare FD. 2004. Dye Bias Correction in Dual-labeled cDNA Microarray Gene Expression Measurements. Environmental Health Perspective Toxicogenomics, 112:480-487.  2004
 
Thompson KL, Afshari CA, Amin RP, Bertram TA, Car B, Cunningham M, Kind C, Kramer JA, Lawton M, Mirsky M, Naciff JM, Oreffo V, Pine PS, and Sistare FD. Identification of Platform-Independent Gene Expression Markers of Cisplatin Nephrotoxicity. Environmental Health Perspective Toxicogenomics, 112:488-494. 2004
 
Ulrich RG, Rockett JC, Gibson GG and Pettit S. Overview of an Inter-Laboratory Collaboration on Evaluating the Effects Model Hepatotoxicants on Hepatic Gene Expression. Environmental Health Perspective Toxicogenomics, 112:423-427. 2004
 
Waring JF, Ulrich RG, Flint N, Morfitt D, Kalkuhl A, Staedtler F, Lawton M, Beekman JM, and Suter L. Interlaboratory Evaluation of Rat Hepatic Gene Expression Changes Induced by Methapyrilene. Environmental Health Perspective Toxicogenomics, 112:439-448. 2004