HESI Application of Genomics to Mechanism-Based Risk Assessment Technical Committee Publications

• Akerman, G.S., et al., Gene expression profiles and genetic damage in benzo(a)pyrene diol epoxide-exposed TK6 cells. Mutat Res, 2004. 549(1-2): p. 43-64.  [Abstract]
   
• Amin, R.P., et al., Identification of putative gene based markers of renal toxicity. Environ Health Perspect, 2004. 112(4): p. 465-79. [Abstract]
   
• Baker, V.A., et al., Clofibrate-induced gene expression changes in rat liver: a cross-laboratory analysis using membrane cDNA arrays. Environ Health Perspect, 2004. 112(4): p. 428-38. [Abstract]
   
• Chu, T.M., et al., Cross-site comparison of gene expression data reveals high similarity. Environ Health Perspect, 2004. 112(4): p. 449-55. [Abstract]
   
• Dickinson, D.A., et al., Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile analysis. Mutat Res, 2004. 549(1-2): p. 29-41. [Abstract]
   
• Goodsaid, F.M., R.J. Smith, and I.Y. Rosenblum, Quantitative PCR deconstruction of discrepancies between results reported by different hybridization platforms. Environ Health Perspect, 2004. 112(4): p. 456-60.  [Abstract] 
   
• Hamadeh, H.K., et al., Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations. Toxicol Pathol, 2002. 30(4): p. 470-82.  [Abstract] 
   
• Hu, T., et al., Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins. Mutat Res, 2004. 549(1-2): p. 5-27.  [Abstract]
   
• Kramer, J.A., et al., Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment. Environ Health Perspect, 2004. 112(4): p. 460-4.  [Abstract]
   
• Mattes, W.B., Annotation and cross-indexing of array elements on multiple platforms. Environ Health Perspect, 2004. 112(4): p. 506-10.  [Abstract]
   
• Mattes, W.B., et al., Database development in toxicogenomics: issues and efforts. Environ Health Perspect, 2004. 112(4): p. 495-505.  [Abstract]
   
• Michael J. Boedigheimer, R.D.W., Michael B. Bass, Pierre R. Bushel, Jeff W. Chou, Matthew Cooper, J. Christopher Corton, Jennifer Fostel, Susan Hester, Janice S. Lee, Fenglong Liu, Jie Liu, Hui-Rong Qian, John Quackenbush, Syril Pettit, and Karol L. Thompson, Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories. BMC Genomics, 2008. 9.  [Abstract]
   
• Muller, A., et al., Laboratory variability does not preclude identification of biological functions impacted by hydroxyurea. Environ Mol Mutagen, 2005. 46(4): p. 221-35.  [Abstract]
   
• Newton, R.K., M. Aardema, and J. Aubrecht, The utility of DNA microarrays for characterizing genotoxicity. Environ Health Perspect, 2004. 112(4): p. 420-2. [Abstract]
   
• Pennie, W., S.D. Pettit, and P.G. Lord, Toxicogenomics in risk assessment: an overview of an HESI collaborative research program. Environ Health Perspect, 2004. 112(4): p. 417-9.  [Abstract]
   
• Pettit, S.D., Toxicogenomics in risk assessment: communicating the challenges. Environ Health Perspect, 2004. 112(12): p. A662.  [Article]
   
• Robinson, D., Pettit, SD, Morgan, DG., Use of Genomics in Mechanism Based Risk Assessment, in Toxicogenomics, T.a.P. Inoue, WD, Eds., Editor. 2003, Springer-Verlag: Tokyo.  [Abstract]
   
• Rosenzweig, B.A., et al., Dye bias correction in dual-labeled cDNA microarray gene expression measurements. Environ Health Perspect, 2004. 112(4): p. 480-7.   [Abstract]
   
• Syril Pettit, E.T., Jean-Pierre Valentin, A HESI Consortium Approach to Assess the Human Predictive Value of Non-Clinical Repolarization Assays. 2009 Jul-Aug;60(1):45-50.  [Abstract]

• Thompson, K.L., et al., Identification of platform-independent gene expression markers of cisplatin nephrotoxicity. Environ Health Perspect, 2004. 112(4): p. 488-94.   [Abstract]

• Ulrich, R.G., et al., Overview of an interlaboratory collaboration on evaluating the effects of model hepatotoxicants on hepatic gene expression. Environ Health Perspect, 2004. 112(4): p. 423-7.  [Abstract]
   
• Waring, J.F., et al., Interlaboratory evaluation of rat hepatic gene expression changes induced by methapyrilene. Environ Health Perspect, 2004. 112(4): p. 439-48.  [Abstract]